SCHEMBL7526236

SCHEMBL7526236

C=Cc1ccccc1C(c1ccccc1)(c1ccccc1)c1c(N)cccc1O

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.35
TSHR P16473 1/20 0.35
PABPC1 P11940 1/20 0.32
APOBEC3A P31941 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7526241 0.81 TSHR (0.37) ALOX15TSHR
SCHEMBL7135788 0.81 ALOX15 (0.48) ALOX15TSHR
SCHEMBL7524048 0.80 ALDH1A1 (0.39) TSHRTRPA1
SCHEMBL7524435 0.78 ALDH1A1 (0.41) ALOX15TSHR
SCHEMBL7519718 0.72 ERN1 (0.46) TSHR
SCHEMBL28725067 0.67 ALDH1A1 (0.44) TSHR
Benzene SCHEMBL23581564 0.66 TRIM24 (0.54) ALOX15TSHRPABPC1APOBEC3AAPOBEC3G
Bromide SCHEMBL7895133 0.66 ALDH1A1 (0.48) ALOX15TSHRAPOBEC3G
Bromide SCHEMBL2361069 0.66 TRIM24 (0.54) ALOX15TRPA1
SCHEMBL7524052 0.66 ALDH1A1 (0.43) TSHRTRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179025-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME Cryovac, Inc. (US) 2002-02-13 EP disclosed
US-6197715-B1 USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS CRYOVAC, INC. 2001-03-06 US disclosed
WO-2000056787-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed