SCHEMBL7526241

SCHEMBL7526241

C=Cc1ccc(C(c2ccccc2)(c2ccccc2)c2c(N)cccc2O)cc1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.36
HDAC2 Q92769 1/20 0.36
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7135788 0.86 ALOX15 (0.48) TSHRALDH1A1ALOX15HDAC2MEN1
SCHEMBL7526236 0.81 ALOX15 (0.35) TSHRALOX15
SCHEMBL7524052 0.76 ALDH1A1 (0.43) TSHRALDH1A1HDAC2MEN1KMT2A
SCHEMBL5200003 0.68 ALDH1A1 (0.54) TSHRALDH1A1HDAC2
SCHEMBL16147388 0.68 GABRA1 (0.46) TSHRALDH1A1MEN1KMT2A
Styrene SCHEMBL29129764 0.67 ALDH1A1 (0.74) TSHRALDH1A1ALOX15MEN1KMT2A
Styrene SCHEMBL27650573 0.67 ALDH1A1 (0.74) TSHRALDH1A1ALOX15HDAC2MEN1
SCHEMBL28719496 0.67 ALDH1A1 (0.65) TSHRALDH1A1
Styrene SCHEMBL25238364 0.65 ALDH1A1 (0.70) TSHRALDH1A1ALOX15MEN1KMT2A
SCHEMBL29066407 0.65 ALDH1A1 (0.50) TSHRALDH1A1ALOX15MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1179025-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME Cryovac, Inc. (US) 2002-02-13 EP disclosed
US-6197715-B1 USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS CRYOVAC, INC. 2001-03-06 US disclosed
WO-2000056787-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed