Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 13/20 | 0.88 |
| ▸ | CTSB | P07858 | 13/20 | 0.88 |
| ▸ | CTSS | P25774 | 13/20 | 0.88 |
| ▸ | CTSK | P43235 | 11/20 | 0.88 |
| ▸ | MME | P08473 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | NPPA | P01160 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533075 | 0.88 | CTSL (1.00) | CTSLCTSBCTSSCTSKSLC6A9 | |
| SCHEMBL7537053 | 0.86 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7569060 | 0.86 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7529726 | 0.84 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7531501 | 0.83 | CTSS (1.00) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7534190 | 0.83 | CTSK (0.91) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7528445 | 0.82 | CTSS (0.74) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7534180 | 0.77 | CTSS (0.52) | CTSLCTSBCTSSCTSKMME | |
| SCHEMBL7530898 | 0.76 | CTSS (0.65) | CTSLCTSBCTSSCTSK | |
| SCHEMBL7530008 | 0.74 | CTSK (0.63) | CTSLCTSBCTSSCTSKMME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |