Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 17/20 | 1.00 |
| ▸ | CTSL | P07711 | 16/20 | 1.00 |
| ▸ | CTSB | P07858 | 15/20 | 1.00 |
| ▸ | CTSK | P43235 | 14/20 | 1.00 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7537053 | 0.95 | CTSS (1.00) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL7531501 | 0.93 | CTSS (1.00) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL7534190 | 0.90 | CTSK (0.91) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL7529726 | 0.89 | CTSS (1.00) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL7533075 | 0.86 | CTSL (1.00) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7526718 | 0.86 | CTSL (0.88) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL7528445 | 0.81 | CTSS (0.74) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL7530137 | 0.77 | CTSS (0.62) | CTSSCTSLCTSBCTSKMME | |
| SCHEMBL7647908 | 0.76 | CTSL (0.68) | CTSSCTSLCTSBCTSK | |
| SCHEMBL7560369 | 0.75 | CTSS (0.67) | CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | claimed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |