SCHEMBL7527728

SCHEMBL7527728

FC(F)(Oc1c[c]ccc1)C(Cl)Cl

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL687497 0.85 PIM1 (0.34) LMNAPOLB
SCHEMBL17134268 0.81 LMNA (0.31) LMNAPOLB
SCHEMBL7705180 0.81 ALDH1A1 (0.45)
SCHEMBL9531099 0.79
SCHEMBL7159968 0.79 ALDH1A1 (0.31)
SCHEMBL8685 0.79 GPR3 (0.34)
SCHEMBL8615049 0.77
SCHEMBL28046395 0.77 GPR3 (0.33)
SCHEMBL9799613 0.77 ALDH1A1 (0.33)
SCHEMBL11643031 0.77 TSHR (0.38) LMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1023299-B1 COMBINED GENERATION OF PHOSPHINIC ACID DERIVATIVES AVENTIS CROPSCIENCE GMBH (DE) 2002-03-27 EP disclosed