Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL687497 | 0.87 | PIM1 (0.34) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL17134268 | 0.83 | LMNA (0.31) | — | |
| SCHEMBL7527728 | 0.81 | LMNA (0.31) | — | |
| SCHEMBL6355243 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TSHRHSD17B10RECQL | |
| SCHEMBL8685 | 0.77 | GPR3 (0.34) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL706601 | 0.77 | TSHR (0.62) | ALDH1A1TSHRHSD17B10RECQL | |
| SCHEMBL17133914 | 0.76 | — | — | |
| SCHEMBL8615049 | 0.76 | — | — | |
| SCHEMBL28046395 | 0.76 | GPR3 (0.33) | ALDH1A1TSHRHSD17B10 | |
| SCHEMBL7474148 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342633-B1 | SULFIDING A CARBONYL COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 2002-01-29 | — | — | US | disclosed |
| US-6211240-B1 | INSECTICIDES | NOVARTIS CORPORATION | 2001-04-03 | — | — | US | disclosed |
| EP-0835242-A1 | THIOAMIDES S-OXIDES FOR USE AS PESTICIDES | Novartis AG (CH) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997000859-A1 | THIOAMIDES S-OXIDES FOR USE AS PESTICIDES | NOVARTIS AG (CH) | 1997-01-09 | — | — | WO | disclosed |