Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526266 | 0.93 | PKM (0.39) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL7532149 | 0.84 | HPGD (0.46) | ALDH1A1HPGDSMN1; SMN2MAPTRAB9A | |
| SCHEMBL7532896 | 0.83 | PKM (0.44) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL7526174 | 0.82 | PKM (0.32) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL708587 | 0.81 | ALDH1A1 (0.42) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL14435485 | 0.79 | SMN1; SMN2 (0.45) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL7529664 | 0.79 | PKM (0.39) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL22661239 | 0.77 | SMN1; SMN2 (0.40) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL8906827 | 0.77 | ALDH1A1 (0.38) | PKMALDH1A1HPGDUSP2SMN1; SMN2 | |
| SCHEMBL7526302 | 0.76 | ABCB1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |