Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7527411 | 0.83 | — | — | |
| SCHEMBL7525276 | 0.81 | POLB (0.30) | POLB | |
| SCHEMBL10455405 | 0.79 | LMNA (0.40) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL7528241 | 0.79 | PKM (0.43) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL7523494 | 0.74 | LMNA (0.49) | PKMALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11057571 | 0.73 | POLB (0.39) | POLB | |
| SCHEMBL7526266 | 0.73 | PKM (0.39) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL7530763 | 0.73 | LMNA (0.48) | PKMALDH1A1SMN1; SMN2HPGDUSP2 | |
| SCHEMBL9190915 | 0.71 | LMNA (0.53) | SMN1; SMN2LMNA | |
| SCHEMBL9287237 | 0.70 | LMNA (0.65) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1186305-A1 | New brominated compounds as contrast media for X-ray mammography | Schering Aktiengesellschaft (DE) | 2002-03-13 | — | — | EP | disclosed |