Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14435475 | 0.85 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL22661239 | 0.84 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL14435477 | 0.81 | LMNA (0.48) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL708587 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL7528241 | 0.79 | PKM (0.43) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL22661232 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL8906827 | 0.75 | ALDH1A1 (0.38) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL7526266 | 0.74 | PKM (0.39) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL29174191 | 0.74 | TSHR (0.48) | SMN1; SMN2ALDH1A1HPGDUSP2PKM | |
| SCHEMBL30807536 | 0.74 | TSHR (0.48) | SMN1; SMN2ALDH1A1HPGDUSP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023117667-A1 | PROCESS FOR THE PREPARATION OF 2,4,6-TRIIODOISOPHTHALIC BISAMIDES | BRACCO IMAGING SPA (IT) | 2023-06-29 | — | — | WO | disclosed |
| WO-2007094683-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2007-08-23 | — | — | WO | disclosed |