Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.31 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL606891 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1CHRM1AKR1A1 | |
| SCHEMBL10774556 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1CHRM1AKR1A1 | |
| SCHEMBL1405990 | 1.00 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1CHRM1AKR1A1 | |
| SCHEMBL687714 | 0.82 | TDP1 (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3837519 | 0.82 | TDP1 (0.42) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL6235619 | 0.82 | TDP1 (0.44) | ALDH1A1TSHRTDP1CHRM1AKR1A1 | |
| SCHEMBL10780881 | 0.82 | TDP1 (0.44) | ALDH1A1TSHRTDP1CHRM1AKR1A1 | |
| SCHEMBL6243346 | 0.79 | CA2 (0.45) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3064781 | 0.78 | PDE4A (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3073651 | 0.78 | PDE4A (0.44) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128213-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-09-12 | — | — | US | disclosed |
| US-20020111317-A1 | Sixteen-membered macrolide compounds | KOSAN BIOSCIENCES, INC. | 2002-08-15 | — | — | US | disclosed |
| WO-2002032916-A2 | SIXTEEN-MEMBERED MACROLIDE COMPOUNDS | KOSAN BIOSCIENCES, INC. (US) | 2002-04-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020111317-A1 | Sixteen-membered macrolide compounds | NOP2, NSUN3, MRPS23 | ALDH1A1 4418/4885TSHR 882/4885TDP1 4354/4885 |
| US-20020128213-A1 | Sixteen-membered macrolide compounds | NOP2, NSUN3, MRPS23 | ALDH1A1 4418/4885TSHR 882/4885TDP1 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.