Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456243 | 0.84 | CES2 (0.42) | CES2CES1F2POLB | |
| SCHEMBL9815889 | 0.82 | CES2 (0.40) | CES2CES1 | |
| SCHEMBL10804236 | 0.79 | CES2 (0.42) | CES2CES1F2POLB | |
| SCHEMBL28938074 | 0.76 | CES2 (0.40) | CES2CES1F2POLB | |
| SCHEMBL812433 | 0.76 | POLB (0.41) | CES2CES1F2POLB | |
| SCHEMBL8918066 | 0.75 | HTT (0.42) | CES2CES1F2POLB | |
| SCHEMBL11749620 | 0.70 | LMNA (0.45) | CES2CES1F2POLB | |
| SCHEMBL4364573 | 0.70 | DPP4 (0.34) | CES2CES1 | |
| SCHEMBL16122071 | 0.70 | CES2 (0.52) | CES2CES1F2POLB | |
| SCHEMBL28939091 | 0.70 | CES2 (0.32) | CES2CES1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1213966-C | Preparation method of aromatic fluorine compounds | NIPPON CATALYTIC CHEM IND (JP) | 2005-08-10 | — | — | CN | disclosed |
| US-6437168-B1 | FLUORINATION; EFFICIENT EXTRACTION | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |
| CN-1342629-A | Preparation method of aromatic fluorine compounds | NIPPON CATALYTIC CHEM IND (JP) | 2002-04-03 | — | — | CN | disclosed |
| US-20020035301-A1 | Method for production of aromatic fluorine compound | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035301-A1 | Method for production of aromatic fluorine compound | AFF4, AFF2, AFF1 | CES2 355/4885CES1 2953/4885F2 35/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.