SCHEMBL753517

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752918	0.90	MAPT (0.43)	KMT2AHTTLMNAPOLBSMN1; SMN2
	SCHEMBL753257	0.88	SMN1; SMN2 (0.39)	KMT2ALMNAHPGDPOLBSMN1; SMN2
	SCHEMBL16921603	0.87	SMN1; SMN2 (0.43)	KMT2AHTTLMNAPOLBSMN1; SMN2
	SCHEMBL752163	0.87	LMNA (0.48)	KMT2ALMNAHPGDPOLBALDH1A1
	Benzylamine SCHEMBL752164	0.86	MAPT (0.40)	KMT2ALMNAPOLBSMN1; SMN2PTGER1
	SCHEMBL16925319	0.86	HTT (0.43)	KMT2AHTTLMNAPOLBSMN1; SMN2
	SCHEMBL751907	0.85	PTGER1 (0.40)	KMT2ALMNAPOLBSMN1; SMN2PTGER1
	SCHEMBL753158	0.85	PTGER1 (0.40)	KMT2ALMNAPOLBSMN1; SMN2PTGER1
	SCHEMBL16921609	0.85	LOXL2 (0.44)	KMT2ALMNAPOLBSMN1; SMN2PTGER1
	SCHEMBL755356	0.84	PTGER1 (0.39)	LMNAPOLBSMN1; SMN2PTGER1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.