SCHEMBL754612

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL752920	0.79	MAOB (0.42)	MAOBALDH1A1NR4A2
	SCHEMBL754255	0.74	CNR2 (0.34)	MAOBALDH1A1
	SCHEMBL756842	0.73	NPC1 (0.60)	NPC1RXFP1RAB9ASMN1; SMN2LTA4H
	SCHEMBL9566786	0.73	CXCR2 (0.57)	NPC1RAB9AP4HTMALDH1A1
	SCHEMBL2933128	0.71	ALDH1A1 (0.41)	ALDH1A1
	SCHEMBL14420953	0.70	POLB (0.46)	RXFP1SMN1; SMN2ALDH1A1
	SCHEMBL13140958	0.70	ALDH1A1 (0.40)	ALDH1A1
	SCHEMBL14811677	0.69	MAPT (0.50)	P4HTMALDH1A1
	SCHEMBL11387130	0.68	P4HTM (0.56)	RAB9ASMN1; SMN2P4HTMALDH1A1GAA
	SCHEMBL24027230	0.68	ALDH1A1 (0.43)	P4HTMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.