SCHEMBL752939

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13098271	0.89	NOS3 (0.50)	KDM4EALDH1A1HPGDNOS1NOS3
	SCHEMBL13754947	0.86	KCNH2 (0.56)	KCNH2ALDH1A1HPGDBACE1MAP2K7
	SCHEMBL24348809	0.83	HTR2B (0.41)	ALDH1A1HPGDMAPK1LMNAHTT
	SCHEMBL13754972	0.82	PTGS1 (0.46)	KCNH2HTT
	SCHEMBL752310	0.78	TDP1 (0.54)	KCNH2KDM4EALDH1A1HPGDBACE1
	SCHEMBL27756279	0.78	KCNH2 (0.47)	KCNH2BACE1MAP2K7NOS1MAPK1
	SCHEMBL6810696	0.78	HTR2A (0.54)	KCNH2BACE1NOS1MAOB
	SCHEMBL13754981	0.78	KCNH2 (0.47)	KCNH2BACE1MAP2K7NOS1MAPK1
	SCHEMBL755313	0.77	TAAR1 (0.58)	KCNH2ALDH1A1MAP2K7MAPK1EGFR
	SCHEMBL14572824	0.77	MAP2K7 (0.47)	KCNH2KDM4EHPGDBACE1MAP2K7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.