Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283714 | 0.83 | CTSL (0.51) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL13177736 | 0.83 | CTSL (0.54) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL12661032 | 0.83 | CTSL (0.54) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL1837974 | 0.82 | ALDH1A1 (0.54) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL7276396 | 0.81 | CTSB (0.47) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL7360632 | 0.81 | CTSL (0.49) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL15461488 | 0.81 | CTSL (0.52) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL1840644 | 0.80 | CTSS (0.59) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL1840338 | 0.80 | CTSK (0.53) | CTSLCTSSCTSBDDB1CRBN | |
| SCHEMBL8296463 | 0.79 | CTSL (0.47) | CTSLCTSSCTSBDDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3019196-B1 | COMBINATIONS OF HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-06-06 | — | — | EP | disclosed |
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |