Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TYMP | P19971 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065649 | 0.89 | HPGD (0.42) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL6837655 | 0.85 | TYMP (0.43) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL8645218 | 0.85 | TK1 (0.42) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL6837969 | 0.78 | TYMP (0.41) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL456749 | 0.78 | HPGD (0.57) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL7529489 | 0.78 | HPGD (0.43) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL28985698 | 0.76 | MAPK1 (0.49) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL27207409 | 0.75 | TYMP (0.41) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL27203667 | 0.75 | TYMP (0.41) | HPGDTYMPMAPK1TK1 | |
| SCHEMBL157965 | 0.75 | TK2 (0.46) | TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761681-B1 | Process for the preparation of substituted derivatives of N-ethylglycine | HOECHST AG (DE) | 2002-03-13 | — | — | EP | disclosed |
| US-5817811-A | AMIDATION OF THE CORRESPOND ESTERIFIED AMINE COMPOUND WITH A CARBOXYLATED NUCLEOTIDE BASE | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-10-06 | — | — | US | disclosed |
| EP-0761681-A2 | Process for the preparation of substituted derivatives of N-ethylglycine | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-12 | — | — | EP | disclosed |