Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.50 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.50 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL227023 | 0.98 | CYP2A6 (0.60) | CYP2A6CYP1A2FLT3LMNAHSD17B1 | |
| SCHEMBL29967341 | 0.98 | CYP2A6 (0.60) | CYP2A6CYP1A2FLT3LMNAHSD17B1 | |
| Ammonia Solution, Strong SCHEMBL8045635 | 0.95 | CYP2A6 (0.58) | CYP2A6CYP1A2FLT3LMNAHSD17B1 | |
| Methyl Alcohol SCHEMBL29235760 | 0.93 | FLT3 (0.57) | CYP2A6CYP1A2FLT3LMNAHSD17B1 | |
| SCHEMBL3138744 | 0.93 | CYP2A6 (0.61) | CYP2A6CYP1A2FLT3LMNAHSD17B1 | |
| SCHEMBL9381604 | 0.88 | CA12 (0.52) | CYP2A6CYP1A2FLT3LMNAHSD17B1 | |
| SCHEMBL1758778 | 0.83 | CYP2A6 (0.48) | CYP2A6CYP1A2FLT3HSD17B1HSD17B2 | |
| SCHEMBL29447161 | 0.83 | CYP1A2 (0.79) | CYP2A6CYP1A2HSD17B1HSD17B2KDM4E | |
| SCHEMBL443070 | 0.83 | CYP1A2 (0.79) | CYP2A6CYP1A2HSD17B1HSD17B2KDM4E | |
| SCHEMBL1129092 | 0.81 | HSD17B1 (0.66) | CYP2A6CYP1A2HSD17B1HSD17B2GSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262845-A1 | PYRIDINIUM SALTS, METHODS OF MAKING, AND METHODS OF USE | UNIV WYOMING (US) | 2024-08-08 | — | — | US | disclosed |
| US-20240262844-A1 | PYRIDINIUM SALTS AND METHODS OF USE | UNIV WYOMING (US) | 2024-08-08 | — | — | US | disclosed |
| WO-2024155935-A2 | PYRIDINIUM SALTS, METHODS OF MAKING, AND METHODS OF USE | UNIVERSITY OF WYOMING (US) | 2024-07-25 | — | — | WO | disclosed |
| EP-0920645-B1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 2002-04-03 | — | — | EP | disclosed |
| WO-2002024619-A1 | AMINE COMPOUNDS | BTG INTERNATIONAL LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |
| US-6096246-A | POLYMER LENSES WITH RADIATION RESISTANT NAPHTHOPYRAN MIXTURES | CORNING INCORPORATED (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0920645-A4 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INC (US) | 1999-08-25 | — | — | EP | disclosed |
| EP-0920645-A1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INCORPORATED (US) | 1999-06-09 | — | — | EP | disclosed |
| WO-1998004937-A1 | NAPHTHOPYRANS, COMPOSITIONS AND ARTICLES CONTAINING THEM | CORNING INCORPORATED (US) | 1998-02-05 | — | — | WO | disclosed |
| US-4496755-A | Optically active 1-(6-methoxy-2-naphthyl)-2-(alkoxycarbonyl) amino-1-propanone, its derivatives and their halo analogs and the methods for their manufacture | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1985-01-29 | — | — | US | disclosed |
| EP-0091757-A1 | Optically active 1-(6-methoxy-2-naphthyl)-2-alkoxycarbonyl)amino-1-propanone, its derivatives and their halo anlogs, and methods for their manufacture | SYNTEX PHARMACEUTICALS INTERNATIONAL LIMITED (BM) | 1983-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262845-A1 | PYRIDINIUM SALTS, METHODS OF MAKING, AND METHODS OF USE | KYNU, TPH1, AADAT | CYP2A6 506/4885CYP1A2 1509/4885FLT3 692/4885 |
| US-20240262844-A1 | PYRIDINIUM SALTS AND METHODS OF USE | KYNU, TPH1, AADAT | CYP2A6 605/4885CYP1A2 1399/4885FLT3 626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.