Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 11/20 | 0.52 |
| ▸ | CTSB | P07858 | 11/20 | 0.52 |
| ▸ | CTSS | P25774 | 11/20 | 0.52 |
| ▸ | CTSK | P43235 | 11/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5105059 | 0.83 | FABP4 (0.51) | CTSLCTSBCTSSCTSKTRPV1 | |
| SCHEMBL1841973 | 0.82 | CNR2 (0.52) | CTSKTRPV1NPC1RAB9A | |
| SCHEMBL7530031 | 0.81 | CTSL (0.49) | CTSLCTSBCTSSCTSKTRPV1 | |
| SCHEMBL1837320 | 0.80 | CNR2 (0.49) | CTSLCTSBCTSSCTSKNPC1 | |
| SCHEMBL12589522 | 0.80 | ALOX15 (0.55) | CTSLNPC1RAB9A | |
| SCHEMBL1836676 | 0.78 | CTSK (0.61) | CTSLCTSBCTSSCTSK | |
| SCHEMBL1976504 | 0.77 | PLK1 (0.55) | NPC1RAB9A | |
| SCHEMBL1813782 | 0.76 | CTSL (0.64) | CTSLCTSBCTSSCTSKNPC1 | |
| SCHEMBL29460240 | 0.74 | TRPV1 (0.48) | TRPV1EPHX2NPC1RAB9ANAMPT | |
| SCHEMBL1838927 | 0.74 | GPR132 (0.50) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002023784-A2 | CYSTEINE PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2002-03-21 | — | — | WO | disclosed |