Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.34 |
| ▸ | PGR | P06401 | 3/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2337166 | 0.84 | CYP19A1 (0.43) | OPRD1MDM2CYP3A4ALOX15 | |
| SCHEMBL3306471 | 0.84 | CYP19A1 (0.43) | OPRD1MDM2CYP3A4ALOX15 | |
| SCHEMBL7521676 | 0.84 | MAPT (0.43) | OPRD1CYP3A4ALOX15ALDH1A1NPSR1 | |
| SCHEMBL7520344 | 0.83 | RET (0.45) | MDM2CYP3A4ALOX15ALDH1A1NPSR1 | |
| SCHEMBL8484519 | 0.82 | CYP19A1 (0.47) | CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL7516218 | 0.81 | MEN1 (0.40) | OPRD1CYP3A4ALOX15OPRM1OPRK1 | |
| SCHEMBL7520906 | 0.80 | KDM4E (0.39) | OPRD1CYP3A4ALOX15OPRM1OPRK1 | |
| SCHEMBL7518991 | 0.79 | TSHR (0.39) | MDM2CYP3A4ALOX15PDK2ALDH1A1 | |
| SCHEMBL7518921 | 0.78 | CYP19A1 (0.37) | CYP3A4ALOX15ALDH1A1 | |
| SCHEMBL7527043 | 0.77 | CHRNA1 (0.45) | CYP3A4ALOX15ALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |