Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | EDNRA | P25101 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ABHD10 | Q9NUJ1 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484519 | 0.88 | CYP19A1 (0.47) | CYP19A1CYP3A4ALOX15RAB9AEDNRA | |
| SCHEMBL7518991 | 0.87 | TSHR (0.39) | CYP19A1CYP3A4ALOX15RAB9AMAPT | |
| SCHEMBL7519457 | 0.86 | TP53 (0.40) | CYP19A1RIPK1EDNRAMAPTKMT2A | |
| SCHEMBL7516852 | 0.83 | ALDH1A1 (0.41) | CYP19A1EDNRAMAPTKDM4EALDH1A1 | |
| SCHEMBL3306471 | 0.80 | CYP19A1 (0.43) | CYP19A1CYP3A4ALOX15RAB9AMAPT | |
| SCHEMBL7521676 | 0.80 | MAPT (0.43) | CYP3A4ALOX15RAB9AMAPTNPC1 | |
| SCHEMBL2337166 | 0.80 | CYP19A1 (0.43) | CYP19A1CYP3A4ALOX15RAB9AMAPT | |
| SCHEMBL7516218 | 0.79 | MEN1 (0.40) | CYP3A4ALOX15RAB9AEDNRAMAPT | |
| SCHEMBL7520344 | 0.79 | RET (0.45) | CYP3A4ALOX15RAB9AMAPTKMT2A | |
| SCHEMBL7530287 | 0.78 | OPRD1 (0.37) | CYP3A4ALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |