Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA1 | P02708 | 7/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 7/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.45 |
| ▸ | CHRNG | P07510 | 5/20 | 0.45 |
| ▸ | CHRND | Q07001 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7520344 | 0.85 | RET (0.45) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL7519643 | 0.83 | MAP3K14 (0.39) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL7522670 | 0.83 | CYP19A1 (0.44) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL7523465 | 0.83 | MAP3K14 (0.39) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL3306471 | 0.79 | CYP19A1 (0.43) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL7521676 | 0.79 | MAPT (0.43) | CYP3A4ALOX15LMNANPSR1TSHR | |
| SCHEMBL2337166 | 0.79 | CYP19A1 (0.43) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL7520578 | 0.78 | GAA (0.43) | CYP3A4ALOX15LMNANPSR1ALDH1A1 | |
| SCHEMBL7520676 | 0.77 | CRHBP (0.37) | CYP3A4ALOX15RETKDRALDH1A1 | |
| SCHEMBL7530287 | 0.77 | OPRD1 (0.37) | CYP3A4ALOX15NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743311-B1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | KAO CORP (JP) | 2002-02-13 | — | — | EP | disclosed |
| US-5876703-A | CELL DIFFERENTIATION OF HAIR MATRIX CELLS | KAO CORPORATION (JP) | 1999-03-02 | — | — | US | disclosed |
| US-5702691-A | Flavanonol derivatives and hair-nourishing, hair growing compositions containing the derivatives | KAO CORPORATION (JP) | 1997-12-30 | — | — | US | disclosed |
| EP-0743311-A1 | FLAVANONOL DERIVATIVES AND HAIR NOURISHMENT AND GROWTH STIMULANT COMPOSITION CONTAINING THE SAME | Kao Corporation (JP) | 1996-11-20 | — | — | EP | disclosed |