Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533926 | 0.94 | TDP1 (0.67) | NPC1TDP1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7536709 | 0.85 | LMNA (0.61) | NPC1TDP1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL12711610 | 0.85 | LMNA (0.61) | NPC1TDP1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7531135 | 0.85 | MEN1 (0.64) | NPC1TDP1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL17913066 | 0.85 | LIMK2 (0.60) | TDP1KDM4EGAAKMT2AMAPT | |
| SCHEMBL23392559 | 0.83 | LMNA (0.55) | NPC1TDP1RAB9AL3MBTL1KMT2A | |
| SCHEMBL23392557 | 0.83 | LMNA (0.55) | NPC1TDP1RAB9AL3MBTL1KMT2A | |
| SCHEMBL7536762 | 0.81 | KMT2A (0.66) | NPC1TDP1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL27286584 | 0.79 | MAPT (0.67) | NPC1TDP1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7538405 | 0.77 | SMN1; SMN2 (0.66) | NPC1RAB9AKDM4EL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |