Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | HTT | P42858 | 2/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12711610 | 0.88 | LMNA (0.61) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7536709 | 0.88 | LMNA (0.61) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL23392559 | 0.85 | LMNA (0.55) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL23392557 | 0.85 | LMNA (0.55) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7530445 | 0.81 | NPC1 (0.60) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL27025915 | 0.81 | ALDH1A1 (0.61) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7531135 | 0.79 | MEN1 (0.64) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL27286584 | 0.78 | MAPT (0.67) | KMT2AMEN1TDP1ALDH1A1MAPT | |
| SCHEMBL7532581 | 0.78 | MAPT (0.59) | KMT2AMEN1ALDH1A1MAPTHTT | |
| SCHEMBL7538405 | 0.77 | SMN1; SMN2 (0.66) | KMT2AMEN1ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |