Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7530445 | 0.94 | NPC1 (0.60) | TDP1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL12711610 | 0.85 | LMNA (0.61) | TDP1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7536709 | 0.85 | LMNA (0.61) | TDP1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL17913066 | 0.80 | LIMK2 (0.60) | TDP1KDM4EGAAMAPTKMT2A | |
| SCHEMBL7531135 | 0.79 | MEN1 (0.64) | TDP1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7536739 | 0.79 | RAB9A (0.48) | TDP1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL23392559 | 0.76 | LMNA (0.55) | TDP1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL23392557 | 0.76 | LMNA (0.55) | TDP1NPC1RAB9AL3MBTL1MAPT | |
| SCHEMBL7536762 | 0.75 | KMT2A (0.66) | TDP1NPC1RAB9AKDM4EL3MBTL1 | |
| SCHEMBL7191924 | 0.74 | ALDH1A1 (0.52) | TDP1NPC1RAB9AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912467-B1 | ASYMMETRIC HYDROGENATION METHOD OF A KETONIC COMPOUND AND DERIVATIVE | RHODIA CHIMIE SA (FR) | 2002-04-24 | — | — | EP | claimed |