SCHEMBL753048

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2483760	0.79	LMNA (0.40)	ALDH1A1L3MBTL1KMT2ALMNAMAPK1
	SCHEMBL2483761	0.79	LMNA (0.40)	ALDH1A1L3MBTL1KMT2ALMNAMAPK1
	SCHEMBL27777092	0.76	MAOB (0.39)	MAOAMAOBALDH1A1L3MBTL1HTR2A
	SCHEMBL25171202	0.76	NPC1 (0.39)	ALDH1A1HTR2AKCNH2LMNAKDM4E
	SCHEMBL753107	0.76	GRM2 (0.41)	ALDH1A1HTR2AKCNH2KMT2ALMNA
	SCHEMBL757225	0.74	P4HTM (0.45)	L3MBTL1KMT2ALMNAMAPK1CASP3
	SCHEMBL217393	0.74	—	—
	SCHEMBL16561361	0.73	IDO1 (0.58)	MAOBALDH1A1LMNAIDO1LOXL2
	SCHEMBL1468357	0.73	IDO1 (0.58)	MAOBALDH1A1LMNAIDO1LOXL2
	SCHEMBL755008	0.73	LTA4H (0.40)	ALDH1A1L3MBTL1KMT2ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.