SCHEMBL757225

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754198	0.81	P4HTM (0.63)	P4HTMLMNAMAPK1CASP3SENP7
	SCHEMBL755141	0.80	MAPT (0.46)	LMNAMAPK1CASP3SENP7SENP6
	SCHEMBL27606156	0.79	P4HTM (0.45)	P4HTMLMNAMAPK1CASP3SENP7
	SCHEMBL754085	0.76	NPSR1 (0.45)	P4HTMLMNAMAPK1CASP3SENP7
	SCHEMBL2483761	0.76	LMNA (0.40)	P4HTMLMNAMAPK1CASP3SENP7
	SCHEMBL2483760	0.76	LMNA (0.40)	P4HTMLMNAMAPK1CASP3SENP7
	SCHEMBL342864	0.76	KMT2A (0.46)	P4HTMLMNAMAPK1CASP3SENP7
	SCHEMBL4465941	0.76	BCL2L1 (0.55)	P4HTM
	SCHEMBL27606384	0.75	LMNA (0.47)	P4HTMLMNAMAPK1CASP3SENP7
	SCHEMBL756391	0.74	HTR2C (0.41)	LMNAMAPK1CASP3SENP7SENP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.