Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 12/20 | 0.62 |
| ▸ | NPC1 | O15118 | 9/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAPDH | P04406 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3397250 | 0.79 | RAB9A (0.61) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL15737243 | 0.78 | ALDH1A1 (0.57) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL1685094 | 0.77 | SMN1; SMN2 (0.59) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL10253097 | 0.77 | RAB9A (1.00) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19145052 | 0.76 | ALDH1A1 (0.71) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL14394393 | 0.76 | NPC1 (0.69) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL19191686 | 0.74 | RAB9A (0.66) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL23965986 | 0.73 | L3MBTL1 (0.68) | RAB9ANPC1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL28033250 | 0.73 | HCAR2 (0.53) | SMN1; SMN2PKMTP53HSD17B10ALOX15 | |
| SCHEMBL15577212 | 0.72 | ALOX15 (0.52) | PKMHSD17B10ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002017358-A2 | QUINUCLIDINE-SUBSTITUTED HETEROARYL MOIETIES FOR TREATMENT OF DISEASE (NICOTINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS) | PHARMACIA & UPJOHN COMPANY (US) | 2002-02-28 | — | — | WO | claimed |