Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | GPR27 | Q9NS67 | 11/20 | 0.56 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.56 |
| ▸ | ACLY | P53396 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.50 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.50 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532994 | 0.81 | GPR27 (0.49) | KMT2AMEN1GPR27AVPR2KDM4E | |
| SCHEMBL7539025 | 0.81 | MEN1 (0.62) | KMT2AMEN1GPR27AVPR2ACLY | |
| SCHEMBL7533594 | 0.79 | KMT2A (0.74) | KMT2AACLYKDM4ECYP3A4PTGS1 | |
| SCHEMBL7530840 | 0.78 | MEN1 (0.62) | KMT2AMEN1GPR27AVPR2KDM4E | |
| Hydrochloric Acid SCHEMBL7533502 | 0.77 | KMT2A (0.72) | KMT2AACLYKDM4ECYP3A4PTGS1 | |
| SCHEMBL7537998 | 0.75 | PGR (0.55) | KMT2AMEN1GPR27AVPR2ACLY | |
| SCHEMBL7531717 | 0.74 | KMT2A (1.00) | KMT2AMEN1ACLYKDM4ECYP3A4 | |
| SCHEMBL31078116 | 0.74 | GPR27 (0.70) | KMT2AMEN1GPR27AVPR2 | |
| SCHEMBL28310266 | 0.74 | LMNA (0.49) | KMT2AMEN1GAAMAPT | |
| SCHEMBL7537677 | 0.74 | KMT2A (0.59) | KMT2AMEN1GPR27AVPR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |