Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | GPR27 | Q9NS67 | 10/20 | 0.57 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.56 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.56 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.56 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531883 | 0.88 | MEN1 (0.60) | MEN1KMT2AKDM4EGPR27AVPR2 | |
| SCHEMBL7534321 | 0.87 | GPR27 (0.55) | MEN1KMT2AKDM4EGPR27AVPR2 | |
| SCHEMBL7533583 | 0.82 | MEN1 (0.50) | MEN1KMT2AKDM4EGPR27AVPR2 | |
| SCHEMBL7532994 | 0.81 | GPR27 (0.49) | MEN1KMT2AKDM4EGPR27AVPR2 | |
| SCHEMBL7533441 | 0.81 | GPR27 (0.49) | MEN1KMT2AKDM4EGPR27GRM4 | |
| SCHEMBL7530848 | 0.80 | GPR27 (0.52) | MEN1KMT2AKDM4EGPR27AVPR2 | |
| SCHEMBL7531393 | 0.80 | SLC10A2 (0.59) | MEN1KMT2AKDM4EGPR27AVPR2 | |
| SCHEMBL7533491 | 0.79 | KMT2A (0.48) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL7533584 | 0.79 | METAP2 (0.56) | MEN1KMT2AKDM4EALDH1A1HTT | |
| SCHEMBL7531362 | 0.78 | KMT2A (0.62) | MEN1KMT2AKDM4EGPR27AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |