Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | GPR27 | Q9NS67 | 10/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.49 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.48 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.47 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561597 | 0.88 | GPR27 (0.54) | KMT2AMEN1GPR27KDM4EGAA | |
| SCHEMBL7537898 | 0.85 | GPR27 (0.54) | KMT2AMEN1GPR27GAAMAPT | |
| SCHEMBL7539025 | 0.79 | MEN1 (0.62) | KMT2AMEN1GPR27KDM4EMAPT | |
| SCHEMBL7539008 | 0.74 | LMNA (0.60) | KMT2AMEN1GPR27KDM4EGAA | |
| SCHEMBL7531362 | 0.74 | KMT2A (0.62) | KMT2AMEN1GPR27KDM4EGAA | |
| SCHEMBL7530840 | 0.74 | MEN1 (0.62) | KMT2AMEN1GPR27KDM4EGRM4 | |
| SCHEMBL7537998 | 0.73 | PGR (0.55) | KMT2AMEN1GPR27KDM4EGRM4 | |
| SCHEMBL7534188 | 0.73 | F10 (0.58) | KMT2AMEN1KDM4EMAPTF10 | |
| SCHEMBL27180378 | 0.71 | GPR27 (0.72) | KMT2AMEN1GPR27KDM4EMAPT | |
| SCHEMBL17593181 | 0.71 | KMT2A (0.92) | KMT2AMEN1GPR27MAPTGRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |