Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945892 | 0.87 | HTR6 (0.40) | HTR6MEN1LMNAMAPTKMT2A | |
| SCHEMBL7473168 | 0.73 | HTR6 (0.41) | HTR6CA1CA2CA9 | |
| SCHEMBL3689324 | 0.70 | KDM4E (0.46) | HTR6MAPTCA2 | |
| SCHEMBL181647 | 0.69 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL788180 | 0.69 | RAPGEF4 (0.38) | MEN1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL7426541 | 0.67 | ALDH1A1 (0.33) | ALDH1A1CA1CA2CA9 | |
| SCHEMBL6957613 | 0.67 | ACLY (0.44) | MEN1LMNAMAPTKMT2AALDH1A1 | |
| SCHEMBL3947273 | 0.66 | HTR6 (0.40) | HTR6CA1CA2 | |
| SCHEMBL3609619 | 0.65 | GAA (0.40) | MEN1KMT2AALDH1A1CA1CA2 | |
| SCHEMBL544443 | 0.65 | CA1 (0.41) | MEN1KMT2AALDH1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1228066-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001032646-A2 | SULFONAMIDE DERIVATIVES | SMITHKLINE BEECHAM P.L.C. (GB) | 2001-05-10 | — | — | WO | disclosed |