Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KCNJ6 | P48051 | 3/20 | 0.43 |
| ▸ | KCNJ5 | P48544 | 3/20 | 0.43 |
| ▸ | KCNJ3 | P48549 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NRP1 | O14786 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7532972 | 0.88 | ACLY (0.47) | ACLYLMNAKCNJ6KCNJ5KCNJ3 | |
| SCHEMBL7532975 | 0.82 | LMNA (0.68) | LMNAKCNJ6KCNJ5KCNJ3ALDH1A1 | |
| SCHEMBL532975 | 0.79 | ACLY (0.69) | ACLYLMNATSHRHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL533067 | 0.78 | ACLY (0.68) | ACLYLMNATSHRHPGDALDH1A1 | |
| SCHEMBL7537245 | 0.77 | LMNA (0.53) | ACLYLMNAHPGDALDH1A1HTT | |
| SCHEMBL7537213 | 0.77 | ACLY (0.53) | ACLYLMNATSHRHPGDALDH1A1 | |
| SCHEMBL7537977 | 0.77 | ACLY (0.52) | ACLYLMNATSHRHPGDALDH1A1 | |
| SCHEMBL7530812 | 0.76 | CYP2C9 (0.52) | ACLYLMNATSHRHPGDALDH1A1 | |
| SCHEMBL7537381 | 0.76 | ALDH1A1 (0.53) | ACLYLMNATSHRHPGDALDH1A1 | |
| SCHEMBL2158425 | 0.75 | ACLY (0.54) | ACLYTSHRHPGDALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |