Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.53 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | NRP1 | O14786 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL532975 | 0.80 | ACLY (0.69) | ALDH1A1ACLYKDM4EHPGDLMNA | |
| Hydrochloric Acid SCHEMBL533067 | 0.79 | ACLY (0.68) | ALDH1A1ACLYKDM4EHPGDLMNA | |
| SCHEMBL7532022 | 0.79 | HPGD (0.57) | ALDH1A1ACLYHPGDHSD17B10MAPT | |
| SCHEMBL7537213 | 0.77 | ACLY (0.53) | ALDH1A1ACLYKDM4EHPGDLMNA | |
| SCHEMBL7532977 | 0.76 | ACLY (0.49) | ALDH1A1ACLYHPGDLMNAHSD17B10 | |
| SCHEMBL7537245 | 0.75 | LMNA (0.53) | ALDH1A1ACLYHPGDLMNAMAPT | |
| Sulfathiazole SCHEMBL7533713 | 0.74 | LMNA (0.67) | ALDH1A1ACLYKDM4ELMNAPKM | |
| SCHEMBL7537977 | 0.74 | ACLY (0.52) | ALDH1A1ACLYHPGDLMNAHSD17B10 | |
| SCHEMBL7533719 | 0.74 | LMNA (0.51) | ACLYHPGDLMNANPSR1NRP1 | |
| SCHEMBL7538001 | 0.74 | ACLY (0.58) | ALDH1A1ACLYHPGDLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |