Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | GOT1 | P17174 | 8/20 | 0.58 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | CCND1 | P24385 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1558997 | 0.78 | MAPT (0.58) | MAPTAVPR1ACDK4CCND1POLB | |
| SCHEMBL1558891 | 0.76 | ALDH1A1 (0.69) | MAPTAVPR1ACDK4CCND1POLB | |
| SCHEMBL612438 | 0.76 | AVPR1A (1.00) | MAPTAVPR1AGAA | |
| SCHEMBL6590682 | 0.75 | DRD2 (0.59) | MAPTAVPR1ACDK4CCND1HTR1A | |
| SCHEMBL7538747 | 0.73 | DRD2 (0.59) | MAPTGAARECQLGOT1HTR1A | |
| SCHEMBL613531 | 0.73 | AVPR1A (0.82) | AVPR1AKDM4EALDH1A1 | |
| SCHEMBL2228008 | 0.73 | GOT1 (0.70) | MAPTGAARECQLGOT1 | |
| SCHEMBL1450182 | 0.73 | GOT1 (0.53) | MAPTGAARECQLGOT1 | |
| SCHEMBL29526941 | 0.72 | GOT1 (1.00) | MAPTGAARECQLGOT1 | |
| SCHEMBL614375 | 0.71 | AVPR1A (0.79) | MAPTAVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020128272-A1 | 4,5,6, and 7-indole and indoline derivatives, their preparation and use | H. LUNDBECK A/S (DK) | 2002-09-12 | — | — | US | disclosed |
| US-6391882-B1 | PSYCHOLOGICAL DISORDERS; ANTIDEPRESSANTS | H. LUNDBECK A/S (DK) | 2002-05-21 | — | — | US | disclosed |
| CN-1336925-A | 4,5,6 and 7-indole and indoline derivatives, their prepn. and use | LUNDBECK & CO AS H (DK) | 2002-02-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128272-A1 | 4,5,6, and 7-indole and indoline derivatives, their preparation and use | HTR2C, HTR1A, HTR7 | MAPT 2061/4885AVPR1A 386/4885GAA 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.