Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.70 |
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.64 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.64 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.64 |
| ▸ | SCN1A | P35498 | 1/20 | 0.64 |
| ▸ | SCN4A | P35499 | 1/20 | 0.64 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.64 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.64 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7531142 | 0.90 | POLB (0.59) | CYP3A4PTGS1SCN3ASCN5ASCN9A | |
| SCHEMBL7530791 | 0.87 | POLB (0.56) | CYP3A4PTGS1SCN3ASCN5ASCN9A | |
| SCHEMBL7531704 | 0.85 | ALDH1A1 (0.57) | CYP3A4PTGS1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7531331 | 0.84 | DHODH (0.55) | CYP3A4PTGS1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7539025 | 0.83 | MEN1 (0.62) | CYP3A4KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7568445 | 0.83 | MEN1 (0.53) | KMT2AMEN1ALDH1A1SMN1; SMN2MAPT | |
| Sulfathiazole SCHEMBL7533713 | 0.83 | LMNA (0.67) | CYP3A4PTGS1SCN3ASCN5ASCN9A | |
| Phthalylsulfathiazole SCHEMBL152662 | 0.82 | CYP3A4 (1.00) | CYP3A4PTGS1SCN3ASCN5ASCN9A | |
| SCHEMBL7533705 | 0.81 | SCN3A (0.56) | CYP3A4PTGS1SCN3ASCN5ASCN9A | |
| SCHEMBL7539041 | 0.80 | MEN1 (0.53) | KMT2AMEN1ALDH1A1MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |