Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.50 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.50 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | FLT1 | P17948 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533361 | 0.89 | ACLY (0.48) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7531331 | 0.89 | DHODH (0.55) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7539025 | 0.88 | MEN1 (0.62) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7537204 | 0.87 | MAPT (0.51) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7539041 | 0.87 | MEN1 (0.53) | MEN1KMT2AALDH1A1AVPR2GPR27 | |
| SCHEMBL7531704 | 0.85 | ALDH1A1 (0.57) | MEN1KMT2AALDH1A1USP2MAPT | |
| SCHEMBL7530740 | 0.85 | MEN1 (0.50) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7534407 | 0.83 | LMNA (0.56) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL7533710 | 0.83 | CYP3A4 (0.70) | MEN1KMT2AALDH1A1KDM4ETDP1 | |
| SCHEMBL7533715 | 0.83 | LMNA (0.52) | MEN1KMT2AALDH1A1KDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |