Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | EDNRA | P25101 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | SCN4A | P35499 | 1/20 | 0.51 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfathiazole SCHEMBL7533713 | 0.89 | LMNA (0.67) | SCN3ACYP3A4PTGS1LMNAALDH1A1 | |
| SCHEMBL3278437 | 0.85 | ALDH1A1 (0.69) | SCN3ALMNAALDH1A1KDM4ECYP2C9 | |
| SCHEMBL7530791 | 0.83 | POLB (0.56) | SCN3ACYP3A4PTGS1LMNAALDH1A1 | |
| SCHEMBL7533710 | 0.81 | CYP3A4 (0.70) | SCN3ACYP3A4PTGS1LMNAALDH1A1 | |
| SCHEMBL532975 | 0.80 | ACLY (0.69) | CYP3A4LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL3130823 | 0.79 | ALDH1A1 (0.67) | SCN3ACYP3A4PTGS1LMNAALDH1A1 | |
| Hydrochloric Acid SCHEMBL533067 | 0.79 | ACLY (0.68) | CYP3A4LMNAALDH1A1KDM4EMEN1 | |
| SCHEMBL7531142 | 0.79 | POLB (0.59) | SCN3ACYP3A4PTGS1LMNAALDH1A1 | |
| SCHEMBL7539012 | 0.79 | LMNA (0.47) | LMNASMN1; SMN2POLBACLYTSHR | |
| SCHEMBL7533711 | 0.78 | LMNA (0.49) | LMNAALDH1A1MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |