Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | LMNA | P02545 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7563545 | 0.94 | CCR2 (0.48) | CCR2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7538052 | 0.88 | SMN1; SMN2 (0.56) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7532769 | 0.88 | MAPT (0.53) | CCR2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7533735 | 0.88 | KMT2A (0.49) | CCR2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7538991 | 0.88 | HTT (0.51) | CCR2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7537030 | 0.85 | MAPT (0.53) | MAPTKMT2AMEN1LMNASMN1; SMN2 | |
| SCHEMBL7537156 | 0.84 | EDNRA (0.51) | CCR2KMT2ALMNAKCNH2TDP1 | |
| SCHEMBL7531761 | 0.83 | MAPT (0.49) | CCR2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7123072 | 0.83 | KMT2A (0.58) | CCR2MAPTKMT2AMEN1LMNA | |
| SCHEMBL7532539 | 0.79 | LMNA (0.53) | MAPTKMT2AMEN1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | claimed |