Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.58 |
| ▸ | MEN1 | O00255 | 9/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | FADS1 | O60427 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.48 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.48 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128109 | 0.87 | MEN1 (0.64) | KMT2AMEN1TSHRMAPTKDM4E | |
| SCHEMBL7213175 | 0.86 | SLC20A2 (0.54) | KMT2AMEN1TSHRMAPTKDM4E | |
| SCHEMBL7208746 | 0.84 | TSHR (0.58) | KMT2AMEN1TSHRMAPTKDM4E | |
| SCHEMBL7533748 | 0.83 | CCR2 (0.53) | KMT2AMEN1MAPTKDM4EGRM4 | |
| SCHEMBL4251978 | 0.80 | NPC1 (0.71) | KMT2AMEN1MAPTKDM4EGRM4 | |
| SCHEMBL7563545 | 0.78 | CCR2 (0.48) | KMT2AMEN1MAPTKDM4EHTT | |
| SCHEMBL28454669 | 0.78 | MEN1 (0.64) | KMT2AMEN1LMNASLC10A2SLC10A1 | |
| SCHEMBL7208733 | 0.77 | SLC10A6 (0.71) | KMT2AMEN1MAPTKDM4EHTT | |
| SCHEMBL20560717 | 0.77 | SLC10A2 (0.70) | KMT2AMEN1MAPTKDM4EHTT | |
| SCHEMBL21328495 | 0.77 | SLC25A1 (0.54) | KMT2AMEN1TSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | claimed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | claimed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | claimed |
| US-20030216449-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-20 | — | — | US | disclosed |
| EP-1202729-A1 | PHOSPHATE TRANSPORT INHIBITORS | SmithKline Beecham Corporation (US) | 2002-05-08 | — | — | EP | disclosed |
| WO-2001087294-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-11-22 | — | — | WO | disclosed |
| WO-2001005398-A1 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216449-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A1, SLC34A3 | KMT2A 4033/4885MEN1 3779/4885TSHR 3074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.