Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | EDNRB | P24530 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 8/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7533748 | 0.94 | CCR2 (0.53) | CCR2MAPTMEN1KMT2ALMNA | |
| SCHEMBL7537156 | 0.91 | EDNRA (0.51) | CCR2KMT2ALMNAEDNRAEDNRB | |
| SCHEMBL7533735 | 0.85 | KMT2A (0.49) | CCR2MAPTMEN1KMT2ALMNA | |
| SCHEMBL7538052 | 0.83 | SMN1; SMN2 (0.56) | MAPTMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL7563215 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL7532769 | 0.83 | MAPT (0.53) | CCR2MAPTMEN1KMT2ALMNA | |
| SCHEMBL7538991 | 0.82 | HTT (0.51) | CCR2MAPTMEN1KMT2ALMNA | |
| SCHEMBL7537030 | 0.82 | MAPT (0.53) | MAPTMEN1KMT2ALMNAMAPK1 | |
| SCHEMBL7562743 | 0.81 | ACLY (0.52) | CCR2MEN1KMT2AACLYNPC1 | |
| SCHEMBL7533017 | 0.81 | LMNA (0.53) | MAPTMEN1KMT2ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002028353-A2 | PHOSPHATE TRANSPORT INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-04-11 | — | — | WO | disclosed |