Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.42 |
| ▸ | RNF4 | P78317 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831239 | 0.84 | TSHR (0.46) | TSHRALDH1A1SMN1; SMN2GAABCL2A1 | |
| SCHEMBL7826288 | 0.84 | MLYCD (0.43) | TSHRALDH1A1SMN1; SMN2TP53OPRM1 | |
| SCHEMBL7831241 | 0.83 | TSPO (0.49) | TSHRALDH1A1SMN1; SMN2GAAPDK2 | |
| SCHEMBL7826854 | 0.79 | PPIB (0.49) | ALDH1A1SMN1; SMN2PDK2NPC1TP53 | |
| SCHEMBL7831271 | 0.74 | ALDH1A1 (0.43) | TSHRALDH1A1SMN1; SMN2GAANPC1 | |
| SCHEMBL10893728 | 0.73 | TRPM8 (0.55) | TSHRALDH1A1RNF4PDK2NPC1 | |
| SCHEMBL14174754 | 0.72 | KDM4E (0.48) | ALDH1A1SMN1; SMN2TP53MAPTMLYCD | |
| SCHEMBL7534269 | 0.72 | TSHR (0.46) | TSHRSMN1; SMN2BCL2A1RNF4PDK2 | |
| SCHEMBL26264796 | 0.72 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2GAAPDK2NPC1 | |
| SCHEMBL14229018 | 0.70 | TP53 (0.55) | ALDH1A1SMN1; SMN2NPC1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5840895-A | INTERMEDIATES FOR ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1998-11-24 | — | — | US | disclosed |
| US-5686442-A | ANTIALLERGENS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-11-11 | — | — | US | disclosed |
| EP-0686636-A1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-12-13 | — | — | EP | disclosed |