Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7528619 | 0.92 | GPR84 (0.48) | GPR84ALOX5NPC1RAB9APIN1 | |
| SCHEMBL7527492 | 0.90 | MAOB (0.40) | GPR84ALOX5NPC1RAB9AKDM4E | |
| SCHEMBL7529928 | 0.85 | GPR84 (0.46) | GPR84ALOX5NPC1RAB9AACACA | |
| SCHEMBL1845591 | 0.80 | KDM4E (0.43) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL7522579 | 0.80 | MEN1 (0.47) | GPR84ALOX5KDM4EKMT2AMEN1 | |
| SCHEMBL23800896 | 0.79 | SLC16A3 (0.41) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL29565491 | 0.79 | SLC16A3 (0.41) | NPC1RAB9AKDM4EKMT2AMEN1 | |
| SCHEMBL1848196 | 0.77 | PLA2G2A (0.41) | KDM4EKMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL6995620 | 0.77 | GPR84 (0.38) | GPR84ALOX5NPC1RAB9AKDM4E | |
| SCHEMBL3701217 | 0.77 | ACACA (0.43) | GPR84NPC1RAB9APIN1ACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020173667-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | TRANSITIONS OPTICAL LIMITED (IE) | 2002-11-21 | — | — | US | claimed |
| US-6478989-B1 | Aromatic substituted naphthopyrans | TRANSITIONS OPTICAL, INC. | 2002-11-12 | — | — | US | claimed |
| US-20020173667-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | TRANSITIONS OPTICAL LIMITED (IE) | 2002-11-21 | — | — | US | disclosed |
| US-6478989-B1 | Aromatic substituted naphthopyrans | TRANSITIONS OPTICAL, INC. | 2002-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173667-A1 | NOVEL AROMATIC SUBSTITUTED NAPHTHOPYRANS | TYR, B3GNT2, PAH | GPR84 3665/4885ALOX5 1994/4885NPC1 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.