SCHEMBL753518

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753281	0.90	LIPG (0.44)	LIPGHSD17B13GAAOPRK1CCR6
	SCHEMBL754533	0.86	SMN1; SMN2 (0.34)	LIPGHSD17B13GAAOPRK1CCR6
	SCHEMBL754596	0.80	LIPG (0.42)	LIPGSMN1; SMN2
	SCHEMBL764988	0.77	GAA (0.35)	LIPGHSD17B13GAAOPRK1CCR6
	SCHEMBL752070	0.76	SMN1; SMN2 (0.43)	LIPGHSD17B13GAAOPRK1CCR6
	SCHEMBL756226	0.75	NR3C2 (0.42)	LIPGLIPC
	SCHEMBL753054	0.73	LIPG (0.39)	LIPGLIPCSMN1; SMN2
	SCHEMBL754144	0.73	LIPG (0.42)	LIPGGAAOPRK1CCR6SMN1; SMN2
	SCHEMBL751203	0.72	LIPG (0.50)	LIPGLIPCGAAOPRK1CCR6
	SCHEMBL752339	0.72	LIPG (0.42)	LIPGSMN1; SMN2NPSR1MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.