SCHEMBL754596

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754144	0.90	LIPG (0.42)	LIPGMEN1KMT2AKCNH2ALDH1A1
	SCHEMBL754752	0.84	USP1 (0.36)	LIPGPTGS1PTGS2MEN1KMT2A
	SCHEMBL754370	0.84	LIPG (0.47)	LIPG
	SCHEMBL753518	0.80	LIPG (0.43)	LIPGSMN1; SMN2
	SCHEMBL755290	0.80	LIPG (0.50)	LIPGKCNH2ALDH1A1
	SCHEMBL756226	0.80	NR3C2 (0.42)	LIPGPTGS1PTGS2DAO
	SCHEMBL752339	0.79	LIPG (0.42)	LIPGALDH1A1SMN1; SMN2
	SCHEMBL753054	0.78	LIPG (0.39)	LIPGPTGS1PTGS2HTR2AKCNH2
	SCHEMBL752082	0.75	LIPG (0.43)	LIPGMEN1KMT2AALDH1A1CYP3A4
	SCHEMBL749812	0.75	NPSR1 (0.33)	LIPGMEN1KMT2AALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.