SCHEMBL753281

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL753518	0.90	LIPG (0.43)	LIPGSMN1; SMN2GAAOPRK1CCR6
	SCHEMBL752070	0.86	SMN1; SMN2 (0.43)	LIPGSMN1; SMN2GAAOPRK1CCR6
	SCHEMBL751203	0.82	LIPG (0.50)	LIPGSMN1; SMN2GAAOPRK1CCR6
	SCHEMBL754144	0.79	LIPG (0.42)	LIPGSMN1; SMN2GAAOPRK1CCR6
	SCHEMBL752339	0.78	LIPG (0.42)	LIPGSMN1; SMN2NPSR1ALDH1A1ABL1
	SCHEMBL754533	0.76	SMN1; SMN2 (0.34)	LIPGSMN1; SMN2GAAOPRK1CCR6
	SCHEMBL755059	0.76	LIPG (0.40)	LIPGSMN1; SMN2GAAOPRK1CCR6
	SCHEMBL754618	0.75	LIPG (0.41)	LIPGSMN1; SMN2GAAOPRK1CCR6
	SCHEMBL754596	0.74	LIPG (0.42)	LIPGSMN1; SMN2MEN1ALDH1A1KMT2A
	SCHEMBL755283	0.73	LIPG (0.47)	LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.