SCHEMBL754144

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL754596	0.90	LIPG (0.42)	LIPGSMN1; SMN2ALDH1A1MEN1KMT2A
	SCHEMBL752339	0.86	LIPG (0.42)	LIPGSMN1; SMN2ALDH1A1NPSR1FYN
	SCHEMBL749812	0.84	NPSR1 (0.33)	LIPGSMN1; SMN2ALDH1A1NPSR1LMNA
	SCHEMBL754370	0.84	LIPG (0.47)	LIPGCASP3SENP7SENP6POLB
	SCHEMBL755290	0.80	LIPG (0.50)	LIPGALDH1A1KCNH2
	SCHEMBL755059	0.80	LIPG (0.40)	LIPGSMN1; SMN2ALDH1A1NPSR1FYN
	SCHEMBL753281	0.79	LIPG (0.44)	LIPGSMN1; SMN2ALDH1A1NPSR1LMNA
	SCHEMBL752082	0.75	LIPG (0.43)	LIPGALDH1A1LMNAMAPK1CASP3
	SCHEMBL754752	0.75	USP1 (0.36)	LIPGSMN1; SMN2ALDH1A1MAPK1POLB
	SCHEMBL756359	0.75	LIPG (0.43)	LIPGLMNAMAPK1L3MBTL1MCHR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.