Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | TK1 | P04183 | 3/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.34 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL735246 | 1.00 | RNASE1 (0.39) | RNASE1TERTTYMSTK1ABCG2 | |
| SCHEMBL6047050 | 0.92 | RNASE1 (0.38) | RNASE1TERTTYMSTK1ABCG2 | |
| SCHEMBL753349 | 0.88 | RNASE1 (0.41) | RNASE1TK1ABCG2TK2ABCB1 | |
| SCHEMBL733918 | 0.88 | RNASE1 (0.41) | RNASE1TK1ABCG2TK2ABCB1 | |
| SCHEMBL6046997 | 0.86 | RNASE1 (0.41) | RNASE1TERTTYMSTK1 | |
| SCHEMBL753347 | 0.80 | RNASE1 (0.47) | RNASE1TYMSTK1ABCG2TK2 | |
| SCHEMBL735528 | 0.80 | TYMS (0.54) | RNASE1TYMSTK1 | |
| SCHEMBL21620261 | 0.80 | RNASE1 (0.41) | RNASE1TK1ABCG2ABCB1 | |
| SCHEMBL734984 | 0.79 | RNASE1 (0.46) | RNASE1TYMSTK1ABCG2TK2 | |
| SCHEMBL25504710 | 0.79 | RNASE1 (0.51) | RNASE1TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138330-B2 | Solid phase synthesis via deblocking immobilized nucleoside, then coupling acyl protected nucleoside phosphoramidite | SIGMA-ALDRICH CO. LLC (US) | 2012-03-20 | — | — | US | disclosed |
| US-20080064867-A1 | PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | SIGMA ALDRICH COMPANY (US) | 2008-03-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080064867-A1 | PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES | RNGTT, DUT, ADAR | RNASE1 154/4885TERT 393/4885TYMS 73/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.