Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681330 | 0.78 | ALDH1A1 (0.59) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7535790 | 0.76 | L3MBTL1 (0.45) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27579266 | 0.76 | CA12 (0.51) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7534716 | 0.74 | ALDH1A1 (0.63) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7235930 | 0.71 | SMN1; SMN2 (0.50) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6674654 | 0.71 | ALDH1A1 (0.59) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6675569 | 0.71 | ALDH1A1 (0.59) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16680267 | 0.71 | SMN1; SMN2 (0.67) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7171823 | 0.71 | HTR6 (0.62) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6680382 | 0.70 | SMN1; SMN2 (0.52) | ALDH1A1LMNAMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020013496-A1 | Benzene compounds as antiproliferative and cholesterol lowering agents | AMGEN INC. | 2002-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013496-A1 | Benzene compounds as antiproliferative and cholesterol lowering agents | CYP46A1, TGFB1, NR1H2 | ALDH1A1 1173/4885LMNA 2006/4885MEN1 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.