Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 3/20 | 0.50 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 2/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3769126 | 0.79 | PGR (0.73) | PGRALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10455160 | 0.78 | PGR (0.75) | PGRALDH1A1IL1RNKEAP1ERAP1 | |
| SCHEMBL10452714 | 0.77 | KMT2A (0.50) | ALDH1A1L3MBTL1MEN1KMT2ALMNA | |
| SCHEMBL7443125 | 0.77 | SLC25A1 (0.68) | CA12CA2CA9PGRSLC25A1 | |
| SCHEMBL410747 | 0.76 | AR (0.67) | CA12CA2CA9L3MBTL1MEN1 | |
| SCHEMBL31235173 | 0.76 | AR (0.67) | CA12CA2CA9L3MBTL1MEN1 | |
| SCHEMBL9763798 | 0.76 | HSP90AA1 (0.42) | CA2ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL7535547 | 0.76 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL10715096 | 0.75 | PGR (0.53) | CA12CA2CA9PGRSLC25A1 | |
| SCHEMBL10422318 | 0.75 | SLC25A1 (0.66) | CA12CA2CA9PGRSLC25A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1349381-A | Sulfonamide derivatives | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-05-15 | — | — | CN | disclosed |