Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HINT1 | P49773 | 4/20 | 0.58 |
| ▸ | NT5E | P21589 | 1/20 | 0.58 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.57 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | GSK3A | P49840 | 2/20 | 0.55 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.55 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.55 |
| ▸ | TGM2 | P21980 | 1/20 | 0.54 |
| ▸ | PNP | P00491 | 1/20 | 0.52 |
| ▸ | KRAS | P01116 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2424287 | 0.92 | HINT1 (0.55) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL7111072 | 0.92 | HINT1 (0.55) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL800400 | 0.92 | TAAR1 (0.58) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL23710670 | 0.92 | TAAR1 (0.58) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL7541561 | 0.92 | TAAR1 (0.56) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL23710671 | 0.92 | TAAR1 (0.58) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL23200375 | 0.92 | TAAR1 (0.58) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL23200376 | 0.92 | TAAR1 (0.58) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL780400 | 0.92 | TAAR1 (0.58) | HINT1NT5ESTING1PDE3BPDE3A | |
| SCHEMBL800874 | 0.92 | TAAR1 (0.58) | HINT1NT5ESTING1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020177695-A1 | Nucleic acid probes and methods | DUKE UNIVERSITY | 2002-11-28 | — | — | US | claimed |
| US-6288221-B1 | REPLACING NUCLEOSIDE WITH DIMETHOXYTRITYL, PHOSPHORAMIDITE, OR HALONUCLEOSIDE DERIVATIVE; ELECTROCHEMICAL OR PHOTOCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES | DUKE UNIVERSITY | 2001-09-11 | — | — | US | claimed |
| CN-118239991-A | Preparation process of high-purity 2-amino-6-chloropurine nucleoside | 甘肃省化工研究院有限责任公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20020177695-A1 | Nucleic acid probes and methods | DUKE UNIVERSITY | 2002-11-28 | — | — | US | disclosed |
| US-6288221-B1 | REPLACING NUCLEOSIDE WITH DIMETHOXYTRITYL, PHOSPHORAMIDITE, OR HALONUCLEOSIDE DERIVATIVE; ELECTROCHEMICAL OR PHOTOCHEMICAL DETECTION OF NUCLEIC ACID SEQUENCES | DUKE UNIVERSITY | 2001-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020177695-A1 | Nucleic acid probes and methods | NUDT1, NT5C3B, NT5C2 | HINT1 96/4885NT5E 9/4885STING1 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.